Treatment-Resistant Depression (TRD)
For adults who have tried two or more antidepressants without adequate relief. SPRAVATO® can interrupt the cycle of partial response and plateaued mood gains.
SPRAVATO® Care
A breakthrough option for adults with treatment-resistant depression—delivered in a calm, private space with continuous monitoring, compassionate support, and full insurance coordination.
Covered by many major insurance plans • Supervised by PMHNP-BC

Clinical Overview
SPRAVATO® (esketamine) is an FDA-approved nasal spray that pairs with an oral antidepressant to target stubborn depressive symptoms through the NMDA receptor pathway—something traditional SSRIs and SNRIs don’t directly address.
For adults who have tried two or more antidepressants without adequate relief. SPRAVATO® can interrupt the cycle of partial response and plateaued mood gains.
Provides a rapidly acting option for adults experiencing significant depressive symptoms alongside active or recent suicidal thoughts.
Because SPRAVATO® acts on glutamate transmission instead of solely on serotonin or norepinephrine, many patients report meaningful improvements within 4–6 weeks along with greater stability, motivation, and clarity.
In-Clinic Flow
SPRAVATO® is administered in clinic under continuous supervision. Each appointment lasts about two hours so we can ensure the medication is working effectively and safely.
You comfortably self-administer the nasal spray while seated in a private treatment suite.
We provide a calm environment with dimmed lights, blankets, and continuous observation while the medication takes effect.
Vitals are monitored at regular intervals. Once you feel steady—and a support person is present—you’re cleared to head home.
Patient Wins
Every nervous system is unique, yet many patients describe the following improvements as they move through the treatment series.
Treatment Timeline
Plans are customized for each person—but here’s the cadence most adults follow as we taper to meet your stability goals.
Builds momentum quickly while your brain creates new glutamate pathways.
Stabilizes gains, reduces symptom spikes, and reinforces new neural connections.
Maintenance visits are tailored to your progress, therapy schedule, and goals.
Insurance & Billing
SPRAVATO® is covered by many major insurance plans. Our dedicated team handles the approvals so you can focus on healing.
Benefit verification and coordination with payers
Prior authorization submissions and tracking
On-going documentation for continued coverage
Transparent billing + patient support every step
Where We Treat
Calm, private suites in Bellevue and Seattle with on-site monitoring, complimentary refreshments, and easy parking.
Phone
425-780-7460Eligibility
You may be a good candidate if you resonate with the following. Every patient receives a comprehensive psychiatric evaluation before beginning treatment.
Tried two or more antidepressants without enough relief
Still experience significant depressive symptoms
Have active or recent suicidal thoughts
Prefer a fast-acting, insurance-supported option
Value structured follow-up with medication + therapy
FAQs
Have more questions? Send us a note through the contact form and a clinician will respond within one business day.
Plan for about two hours in clinic. This covers self-administration, a restful recovery period, snack/refreshment time, and our final safety check before you leave with a support person.
Many commercial plans and select public plans cover SPRAVATO®. We verify benefits, submit authorizations, and manage documentation so there are no surprises.
SPRAVATO® is the only FDA-approved esketamine nasal spray. It’s administered in clinic with strict safety protocols and insurance support. IV ketamine is an off-label infusion that is typically self-pay.
No. You’ll need a trusted support person to drive you home and stay with you for the remainder of the day. Most patients feel back to baseline the following morning.
Some patients notice mood shifts within the first few sessions. Most experience significant improvement between weeks 4–6 when the full treatment schedule is followed.
Temporary dissociation, dizziness, or mild nausea can occur shortly after dosing. We monitor vitals, provide comfort measures, and symptoms typically resolve before discharge.
Ready to begin?
Request your SPRAVATO® consultation today.